Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
December 2006
Contract and move
Endosomes generate Rho–ROCK–MLC2-based contractile signals that promote adhesion dissasembly and cell motility.
Original research paper: J. Cell Biol. 175, 337-347
(2006)Anticancer drugs: Downstream GPCR inhibition
A novel anticancer agent that selectively inhibits the heterotrimeric G-protein subunit complex inhibits Wnt-induced cancer cell invasion.
Original research paper: Cancer Res. 66, 9227-9234
(2006)Epigenetics: Imprinting links embryogenesis and tumour formation
Researchers identify a network of imprinted genes that are involved in the control of embryonic growth, and potentially in tumour development.
Original research paper: Dev. Cell 11, 711-722
(2006)SIMS for membranes
By combining two imaging methods researchers are able to investigate membrane complexity and lipid distribution at high spatial resolution.
Original research paper: Nat. Methods 3, 1007-1012 (2006)