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Research Highlights

Short, accessible highlights that summarize and put into context must-read papers related to cell migration.

  • January 2006

    • Setting up shop

      The migration of bone marrow-derived cells to specific tissues helps to establish an environment that attracts tumour cells and promotes the growth of metastases.

      Original research paper: Nature 438, 820-827
      (2005)

    • Controlling gene expression in time and space

      An inducible expression system that allows temporal and dosage control of genes can be used to study how gene expression gradients influence embyronic development.

      Original research paper: Cell 123, 449-461
      (2005)

    • Pathway paradox

      Two studies now show that the serine/threonine kinase AKT can block cancer cell migration and invasion.

      Original research paper: Mol. Cell, 20, 539-550 (2005)
      JCB, 171, 1023-1034 (2005)

    • Together at last: crystallography and NMR

      In a collaborative effort to determine the three-dimensional structures of small proteins, two studies demonstrate that X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy are complementary techniques.

      Original research paper: J. Am. Chem. Soc. 127, 16505-16511 & 16512-16517 (2005)

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