Research Highlights
Short, accessible highlights that summarize and put into context must-read papers related to cell migration.
October 2005
Angiogenesis: Alternative pathways
Interleukin-8 (IL-8) can induce angiogenesis in the absence of oxygen and of the hypoxia-inducible factor-1 (HIF1).
Original research paper: Nature Med.,
(21 Aug 2005); doi:10.1038/nm1294Gene networks: Testing the network
A new automated method that prioritizes deletion experiments may help validate predicted protein−protein interactions and resolve ambiguous models.
Original research paper: Genome Biol. 6, R62
(2005)Metastasis: Destination control
Microarray analysis has identified 54 genes that selectively mediate the metastasis of breast cancer cells to the lung.
Original research paper: Nature 436, 518-524
(2005)Signal transduction: What's in a name?
Far from doing what its name suggests, the intracellular protein prohibitin actually promotes epithelial cell migration by activating the Ras−Raf signaling pathway.
Original research paper: Nature Cell Biol. 7, 837-843
(2005)Miniature movers take on heavy lifting
Researchers are making use of chemotactic unicellular algae to transport micro- and nanoscale objects.
Original research paper: Proc. Natl. Acad. Sci. USA 102, 11963–11967
(2005)