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Welcome to the February 2010 Cell Migration Update, your one-stop resource for news, highlights and research on cell migration.

FEATURED ARTICLES

Specially written Editor's reviews of the hottest new articles

Tumour cell invasion: p53 and integrin duet

Mutant p53 promotes cancer cell invasion and random motility by enhancing integrin recycling.

Iley Ozerlat Original research paper: Cell 139, 1327-1341 (2009)

Wound healing: Occludin polarizes the leading edge

Occludin keeps polarity proteins at the leading edge, and regulates lamellipodia formation and directional migration during wound healing.

Iley Ozerlat Original research paper: Developmental Cell 18, 52-63 (2010)

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RESEARCH HIGHLIGHTS

Synopses of important recent articles

To adhere or not to adhere?

Non-adhesive cell migration in 3D tissues.

Peter FriedlNature Reviews Molecular Cell Biology 11, 3 (2010)

Metastasis: Self-renewal migrates onwards

Expression of ZEB1 in cancer cells enables epithelial to mesenchymal transition (EMT) and stem-cell like properties, forming migrating tumour stem cells.

Nicola MccarthyNature Reviews Cancer 10, 6 - 7 (2010)

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NEWS

The latest news selected from the CMC, Nature News and journals from the Nature family

Consortium Update

Consortium February Update

Cell migration: Signalling for persistence.

Stem-cell line given the nod

NIH moves to approve cells in limbo after rule change.


CELL MIGRATION KNOWLEDGEBASE

From Zamir & Geiger 2001; J. Cell Sc. 114:3583-90. Reproduced with permission from the Company of Biologists.

Visit the Cell Migration Knowledgebase for the latest cell migration protein database entries.

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CONSORTIUM ACTIVITIES

From Nalbant et al. 2004; Science 305:1615-19. Reprinted with permission from AAAS.

Find out more about the Consortium activities, and the latest Consortium Updates.