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Consortium Updates

Welcome to the Cell Migration Consortium's updates page, where we highlight major additions of data and information, and outline some of the publications appearing as a result of the Consortium's activities.

Archive

  1. 2002
  2. 2003
  3. 2004
  4. 2005
  5. 2006
  6. 2007
  7. 2008
  8. 2009
  9. 2010
  10. 2011
  11. 2012

  • November 2004

    1. Image Correlation Microscopy

    • Image Correlation Microscopy

      Image Correlation Microscopy (ICM) was used to develop cellular maps of integrin clustering, diffusion and interactions in the cell. Two color ICM shows that alpha5 integrin and alpha-actinin localize and move together even in regions of the cell with no discernable adhesions.

      • Wiseman PW, Brown CM, Webb DJ, Hebert B, Johnson NL, Squier JA, Ellisman MH, Horwitz AF. Spatial mapping of integrin interactions and dynamics during cell migration by Image Correlation Microscopy. J Cell Sci. 2004;117(Pt 23):5521-34. PubMed
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  • October 2004

    1. Visualization of endogenous Cdc42 activation in living cells.

    • Visualization of endogenous Cdc42 activation in living cells.

      A novel domain-environment sensitive fluorophore allows the visualization of endogenous Cdc42 activation in living cells.

      • Nalbant P, Hodgson L, Kraynov V, Toutchkine A, Hahn KM. Activation of endogenous Cdc42 visualized in living cells. Science. 2004;305(5690):1615-9. PubMed
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  • July 2004

    1. Structural basis of Vinculin activation

    • Structural basis of Vinculin activation

      High resolution structural analysis reveals the basis for vinculin activation.

      • Bakolitsa C, Cohen DM, Bankston LA, Bobkov AA, Cadwell GW, Jennings L, Critchley DR, Craig SW, Liddington RC. Structural basis for vinculin activation at sites of cell adhesion. Nature. 2004;430(6999):583-6. PubMed
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2004